blisa: Bivariate Local Indicator of Spatial Association for spatial transcriptomics

Identifies cell-cell communication hotspots in spatial transcriptomics data using bivariate Local Moran's I statistics on hexagonally binned cells. Provides functions for spatial weighting, ligand-receptor pair filtering, hotspot detection, and visualisation of sender-receiver cell-type interactions.

See also

Useful links:

• https://github.com/ChenLaboratory/blisa

• https://chenlaboratory.github.io/blisa/

• Report bugs at https://github.com/ChenLaboratory/blisa/issues

Author

Maintainer: Yunshun Chen yuchen@wehi.edu.au

Authors:

• Lei Qin qin.l@wehi.edu.au

• Lizhong Chen